Evaluation of Immune Response to rσB Protein of Avian reovirus (ARV) in Chicken

Avian reovirus (ARV) belongs to the genus Orthoreovirus in the family Reoviridae and was first isolated from birds in 1954 (Fahey and Crawley, 1954). Virus particles are 70 nm to 80 nm in size, non-enveloped and have icosahedral symmetry with a double-shelled arrangement of surface protein. The genome of the virus is dsRNA with 10 segments. Depending on their electrophoretic mobility the genome segments are divided into three size classes large (L1, L2, L3), medium (M1, M2, M3), and small (S1, S2, S3, S4) (Spandidos and Graham, 1976). Similarly, proteins encoded by the genome also fall into 3 size classes, as follows:  (large),  (medium) and  (small). The ARV genome International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 4 (2017) pp. 1496-1507 Journal homepage: http://www.ijcmas.com